LUNA Beauty GHK-Cu 50mg

GHK-Cu is a naturally occurring copper-binding peptide made up of 3 amino acids with a powerful role in cellular regeneration and repair. It functions as a signaling molecule that modulates gene expression, influencing over 4,000 human genes related to tissue remodeling, inflammation regulation, and antioxidant defense. This peptide enhances the activity of enzymes like superoxide dismutase (SOD), which neutralize oxidative stress, and promotes collagen synthesis, angiogenesis, and extracellular matrix regeneration. It also supports the proliferation of fibroblasts, improves blood vessel integrity, and plays a role in neuro-regeneration and immune modulation.

Therapeutic Applications

• Skin healing and anti-aging
• Hair regrowth and follicle regeneration
• Wound repair and scar reduction
• Muscle and connective tissue recovery
• Neuroinflammation and nervous system repair
• Immune regulation and antioxidant support
• Post-surgical recovery (cosmetic or reconstructive)
• Skin barrier restoration and hydration

Side Effects

• Generally, very well tolerated
• Rare cases of mild irritation at injection site or topical application
• Theoretical risk of copper overload is minimal due to tight regulatory balance in the GHK complex with topical treatments
• Abuse of injectable solutions can lead to toxicity
• Lunula of the nail may turn blue (corrects over 4-6 weeks)
• No known toxicity at therapeutic doses
• High doses may affect zinc absorption

Use Cases

• Skin healing and aesthetics: Frequently used in dermatology and cosmetic medicine to improve skin elasticity, reduce fine lines and wrinkles, and support scar remodeling. GHK-Cu promotes collagen and glycosaminoglycan synthesis, supporting dermal thickness and hydration.
• Hair regrowth: Shown to enhance hair follicle size, increase hair count, and extend the anagen (growth) phase. Commonly paired with micro-needling, red light therapy, or topical application for best results.
• Stem cell support: Promotes the proliferation, migration, and differentiation of stem cells, particularly in damaged or inflamed tissue environments. This supports regenerative processes in musculoskeletal, neurological, and epithelial tissues.
• Tissue recovery: Often included in injury and surgical healing protocols to improve tissue remodelling and reduce inflammation, especially when stacked with peptides like BPC-157 or TB-500.
• Neurological support: Investigated for its potential to support neural regeneration, reduce oxidative stress in the brain, and protect against excitotoxic damage in conditions involving neuroinflammation.
• Wound care and tissue remodelling: Used in clinical settings for burns, ulcers, and surgical wounds. GHK-Cu enhances angiogenesis and speeds up the remodelling phase of healing, improving tissue integrity and minimizing scarring.